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A comparative analysis of the fluorescence properties of the wild-type and active site mutants of the hepatitis C virus autoprotease NS2-3

Hepatitis C virus encodes an autoprotease, NS2-3, which is required for processing of the viral polyprotein between the non-structural NS2 and NS3 proteins. This protease activity is vital for the replication and assembly of the virus and therefore represents a target for the development of anti-vir...

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Detalles Bibliográficos
Autores principales:	Foster, Toshana L., Tedbury, Philip R., Pearson, Arwen R., Harris, Mark
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier Pub. Co 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824112/ https://www.ncbi.nlm.nih.gov/pubmed/19853065 http://dx.doi.org/10.1016/j.bbapap.2009.10.006

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