Enhanced tonic GABA(A) inhibition in typical absence epilepsy

The cellular mechanisms underlying typical absence seizures, which characterize various idiopathic generalized epilepsies, are not fully understood, but impaired GABAergic inhibition remains an attractive hypothesis. In contrast, we show here that extrasynaptic GABA(A) receptor–dependent ‘tonic’ inh...

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Detalles Bibliográficos
Autores principales: Cope, David W., Di Giovanni, Giuseppe, Fyson, Sarah J., Orbán, Gergely, Errington, Adam C., Lőrincz, Magor L., Gould, Timothy M., Carter, David A., Crunelli, Vincenzo
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824149/
https://www.ncbi.nlm.nih.gov/pubmed/19966779
http://dx.doi.org/10.1038/nm.2058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824149/
https://www.ncbi.nlm.nih.gov/pubmed/19966779
http://dx.doi.org/10.1038/nm.2058

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