Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To investigate ERK activation in real time, we expressed an ERK–GFP fusion protein in human mammary epithelial cells. On EGF stimulation, we obse...

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Detalles Bibliográficos
Autores principales: Shankaran, Harish, Ippolito, Danielle L, Chrisler, William B, Resat, Haluk, Bollinger, Nikki, Opresko, Lee K, Wiley, H Steven
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824491/
https://www.ncbi.nlm.nih.gov/pubmed/19953086
http://dx.doi.org/10.1038/msb.2009.90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824491/
https://www.ncbi.nlm.nih.gov/pubmed/19953086
http://dx.doi.org/10.1038/msb.2009.90

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