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Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor
Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To investigate ERK activation in real time, we expressed an ERK–GFP fusion protein in human mammary epithelial cells. On EGF stimulation, we obse...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824491/ https://www.ncbi.nlm.nih.gov/pubmed/19953086 http://dx.doi.org/10.1038/msb.2009.90 |