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Deciphering a transcriptional regulatory code: modeling short-range repression in the Drosophila embryo

Systems biology seeks a genomic-level interpretation of transcriptional regulatory information represented by patterns of protein-binding sites. Obtaining this information without direct experimentation is challenging; minor alterations in binding sites can have profound effects on gene expression,...

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Detalles Bibliográficos
Autores principales: Fakhouri, Walid D, Ay, Ahmet, Sayal, Rupinder, Dresch, Jacqueline, Dayringer, Evan, Arnosti, David N
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824527/
https://www.ncbi.nlm.nih.gov/pubmed/20087339
http://dx.doi.org/10.1038/msb.2009.97