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Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma

BACKGROUND: The cyclin D1 (CCND1) and cyclin D3 (CCND3) are frequently co-overexpressed in pancreatic ductal adenocarcinoma (PDAC). Here we examine their differential roles in PDAC. RESULTS: CCND1 and CCND3 expression were selectively suppressed by shRNA in PDAC cell lines with expression levels of...

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Detalles Bibliográficos
Autores principales: Radulovich, Nikolina, Pham, Nhu-An, Strumpf, Dan, Leung, Lisa, Xie, Wing, Jurisica, Igor, Tsao, Ming-Sound
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824633/
https://www.ncbi.nlm.nih.gov/pubmed/20113529
http://dx.doi.org/10.1186/1476-4598-9-24