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Suppression of LPS-induced inflammatory responses in macrophages infected with Leishmania

BACKGROUND: Chronic inflammation activated by macrophage innate pathogen recognition receptors such as TLR4 can lead to a range of inflammatory diseases, including atherosclerosis, Crohn's disease, arthritis and cancer. Unlike many microbes, the kinetoplastid protozoan pathogen Leishmania has b...

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Detalles Bibliográficos
Autores principales: Lapara, Nicholas J, Kelly, Ben L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824668/
https://www.ncbi.nlm.nih.gov/pubmed/20205812
http://dx.doi.org/10.1186/1476-9255-7-8