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Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
BACKGROUND: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this should ideally be achieved by testing two separate null hypotheses, current methods treat both hypotheses as one. The fi...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824674/ https://www.ncbi.nlm.nih.gov/pubmed/20064243 http://dx.doi.org/10.1186/1471-2105-11-19 |