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Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model

BACKGROUND: Angiogenesis is the formation of neovasculature from a pre-existing vascular network. Progression of solid tumors including lung cancer is angiogenesis-dependent. We previously introduced a bioinformatics-based methodology to identify endogenous anti-angiogenic peptide sequences, and val...

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Detalles Bibliográficos
Autores principales: Koskimaki, Jacob E, Karagiannis, Emmanouil D, Tang, Benjamin C, Hammers, Hans, Watkins, D Neil, Pili, Roberto, Popel, Aleksander S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824711/
https://www.ncbi.nlm.nih.gov/pubmed/20122172
http://dx.doi.org/10.1186/1471-2407-10-29