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Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
BACKGROUND: Epigenetic changes associated with promoter DNA methylation results in silencing of several tumor suppressor genes that lead to increased risk for tumor formation and for progression of the cancer. METHODS: Methylation specific PCR (MSP) and bisulfite sequencing were used for determinati...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824712/ https://www.ncbi.nlm.nih.gov/pubmed/20132554 http://dx.doi.org/10.1186/1471-2407-10-32 |