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Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation

BACKGROUND: Epigenetic changes associated with promoter DNA methylation results in silencing of several tumor suppressor genes that lead to increased risk for tumor formation and for progression of the cancer. METHODS: Methylation specific PCR (MSP) and bisulfite sequencing were used for determinati...

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Detalles Bibliográficos
Autores principales:	Wu, Yanyuan, Alvarez, Monica, Slamon, Dennis J, Koeffler, Phillip, Vadgama, Jaydutt V
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824712/ https://www.ncbi.nlm.nih.gov/pubmed/20132554 http://dx.doi.org/10.1186/1471-2407-10-32

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