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Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells

BACKGROUND: Previously we found that Rad54/Rad54B cells are more sensitive towards mitomycin C (MMC) as compared to wild-type (WT) cells. This difference in sensitivity was absent upon exposure to other clastogens like bleomycin (BLM) and γ-radiation. In order to get further insight into possible un...

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Detalles Bibliográficos
Autores principales: Mahabir, Anuska G, Schaap, Mirjam M, Pennings, Jeroen LA, van Benthem, Jan, Hendriksen, Coenraad FM, van Steeg, Harry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824718/
https://www.ncbi.nlm.nih.gov/pubmed/20067618
http://dx.doi.org/10.1186/1471-2164-11-24