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Gene prioritization in Type 2 Diabetes using domain interactions and network analysis

BACKGROUND: Identification of disease genes for Type 2 Diabetes (T2D) by traditional methods has yielded limited success. Based on our previous observation that T2D may result from disturbed protein-protein interactions affected through disrupting modular domain interactions, here we have designed a...

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Detalles Bibliográficos
Autores principales: Sharma, Amitabh, Chavali, Sreenivas, Tabassum, Rubina, Tandon, Nikhil, Bharadwaj, Dwaipayan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824729/
https://www.ncbi.nlm.nih.gov/pubmed/20122255
http://dx.doi.org/10.1186/1471-2164-11-84