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Identifying the Rules of Engagement Enabling Leukocyte Rolling, Activation, and Adhesion
The LFA-1 integrin plays a pivotal role in sustained leukocyte adhesion to the endothelial surface, which is a precondition for leukocyte recruitment into inflammation sites. Strong correlative evidence implicates LFA-1 clustering as being essential for sustained adhesion, and it may also facilitate...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824748/ https://www.ncbi.nlm.nih.gov/pubmed/20174606 http://dx.doi.org/10.1371/journal.pcbi.1000681 |