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IFN-α-Induced Upregulation of CCR5 Leads to Expanded HIV Tropism In Vivo
Chronic immune activation and inflammation (e.g., as manifest by production of type I interferons) are major determinants of disease progression in primate lentivirus infections. To investigate the impact of such activation on intrathymic T-cell production, we studied infection of the human thymus i...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824759/ https://www.ncbi.nlm.nih.gov/pubmed/20174557 http://dx.doi.org/10.1371/journal.ppat.1000766 |