Analysis of the role of PCNA-DNA contacts during clamp loading

BACKGROUND: Sliding clamps, such as Proliferating Cell Nuclear Antigen (PCNA) in eukaryotes, are ring-shaped protein complexes that encircle DNA and enable highly processive DNA replication by serving as docking sites for DNA polymerases. In an ATP-dependent reaction, clamp loader complexes, such as...

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Detalles Bibliográficos
Autores principales: McNally, Randall, Bowman, Gregory D, Goedken, Eric R, O'Donnell, Mike, Kuriyan, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824762/
https://www.ncbi.nlm.nih.gov/pubmed/20113510
http://dx.doi.org/10.1186/1472-6807-10-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824762/
https://www.ncbi.nlm.nih.gov/pubmed/20113510
http://dx.doi.org/10.1186/1472-6807-10-3

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