Exploring the Gain of Function Contribution of AKT to Mammary Tumorigenesis in Mouse Models

Elevated expression of AKT has been noted in a significant percentage of primary human breast cancers, mainly as a consequence of the PTEN/PI3K pathway deregulation. To investigate the mechanistic basis of the AKT gain of function-dependent mechanisms of breast tumorigenesis, we explored the phenoty...

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Detalles Bibliográficos
Autores principales: Blanco-Aparicio, Carmen, Cañamero, Marta, Cecilia, Yolanda, Pequeño, Belén, Renner, Oliver, Ferrer, Irene, Carnero, Amancio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824815/
https://www.ncbi.nlm.nih.gov/pubmed/20174572
http://dx.doi.org/10.1371/journal.pone.0009305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824815/
https://www.ncbi.nlm.nih.gov/pubmed/20174572
http://dx.doi.org/10.1371/journal.pone.0009305

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