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Exploring the Gain of Function Contribution of AKT to Mammary Tumorigenesis in Mouse Models
Elevated expression of AKT has been noted in a significant percentage of primary human breast cancers, mainly as a consequence of the PTEN/PI3K pathway deregulation. To investigate the mechanistic basis of the AKT gain of function-dependent mechanisms of breast tumorigenesis, we explored the phenoty...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824815/ https://www.ncbi.nlm.nih.gov/pubmed/20174572 http://dx.doi.org/10.1371/journal.pone.0009305 |