Tumor Transcriptome Sequencing Reveals Allelic Expression Imbalances Associated with Copy Number Alterations

Due to growing throughput and shrinking cost, massively parallel sequencing is rapidly becoming an attractive alternative to microarrays for the genome-wide study of gene expression and copy number alterations in primary tumors. The sequencing of transcripts (RNA-Seq) should offer several advantages...

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Detalles Bibliográficos
Autores principales: Tuch, Brian B., Laborde, Rebecca R., Xu, Xing, Gu, Jian, Chung, Christina B., Monighetti, Cinna K., Stanley, Sarah J., Olsen, Kerry D., Kasperbauer, Jan L., Moore, Eric J., Broomer, Adam J., Tan, Ruoying, Brzoska, Pius M., Muller, Matthew W., Siddiqui, Asim S., Asmann, Yan W., Sun, Yongming, Kuersten, Scott, Barker, Melissa A., De La Vega, Francisco M., Smith, David I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824832/
https://www.ncbi.nlm.nih.gov/pubmed/20174472
http://dx.doi.org/10.1371/journal.pone.0009317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824832/
https://www.ncbi.nlm.nih.gov/pubmed/20174472
http://dx.doi.org/10.1371/journal.pone.0009317

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