SUMOylation regulates the nuclear mobility of CREB binding protein and its association with nuclear bodies in live cells

The lysine acetyltransferase CREB binding protein (CBP) is required for chromatin modification and transcription at many gene promoters. In fixed cells, a large proportion of CBP colocalises to PML or nuclear bodies. Using live cell imaging, we show here that YFP-tagged CBP expressed in HEK293 cells...

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Detalles Bibliográficos
Autores principales: Ryan, Colm M., Kindle, Karin B., Collins, Hilary M., Heery, David M.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824845/
https://www.ncbi.nlm.nih.gov/pubmed/20006587
http://dx.doi.org/10.1016/j.bbrc.2009.12.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824845/
https://www.ncbi.nlm.nih.gov/pubmed/20006587
http://dx.doi.org/10.1016/j.bbrc.2009.12.040

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