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SUMOylation regulates the nuclear mobility of CREB binding protein and its association with nuclear bodies in live cells
The lysine acetyltransferase CREB binding protein (CBP) is required for chromatin modification and transcription at many gene promoters. In fixed cells, a large proportion of CBP colocalises to PML or nuclear bodies. Using live cell imaging, we show here that YFP-tagged CBP expressed in HEK293 cells...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824845/ https://www.ncbi.nlm.nih.gov/pubmed/20006587 http://dx.doi.org/10.1016/j.bbrc.2009.12.040 |