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Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion

BACKGROUND: Factors responsible for invasive and metastatic progression of prostate cancer (PCa) remain largely unknown. Previously, we reported cloning of prosaposin (PSAP) and its genomic amplification and/or overexpression in several androgen-independent metastatic PCa cell lines and lymph node m...

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Detalles Bibliográficos
Autores principales: Hu, Siyi, Delorme, Nathalie, Liu, Zhenzhen, Liu, Tao, Velasco-Gonzalez, Cruz, Garai, Jone, Pullikuth, Ashok, Koochekpour, Shahriar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825248/
https://www.ncbi.nlm.nih.gov/pubmed/20132547
http://dx.doi.org/10.1186/1476-4598-9-30