Whole Methylome Analysis by Ultra-Deep Sequencing Using Two-Base Encoding

Methylation, the addition of methyl groups to cytosine (C), plays an important role in the regulation of gene expression in both normal and dysfunctional cells. During bisulfite conversion and subsequent PCR amplification, unmethylated Cs are converted into thymine (T), while methylated Cs will not...

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Detalles Bibliográficos
Autores principales: Bormann Chung, Christina A., Boyd, Victoria L., McKernan, Kevin J., Fu, Yutao, Monighetti, Cinna, Peckham, Heather E., Barker, Melissa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825269/
https://www.ncbi.nlm.nih.gov/pubmed/20179767
http://dx.doi.org/10.1371/journal.pone.0009320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825269/
https://www.ncbi.nlm.nih.gov/pubmed/20179767
http://dx.doi.org/10.1371/journal.pone.0009320

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