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Direct Observation and Quantitative Analysis of Lck Exchange between Plasma Membrane and Cytosol in Living T Cells

Palmitoylation represents a common motif for anchorage of cytosolic proteins to the plasma membrane. Being reversible, it allows for controlled exchange between cytosolic and plasma membrane-bound subpopulations. In this study, we present a live cell single molecule approach for quantifying the exch...

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Detalles Bibliográficos
Autores principales: Zimmermann, Lars, Paster, Wolfgang, Weghuber, Julian, Eckerstorfer, Paul, Stockinger, Hannes, Schütz, Gerhard J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825400/
https://www.ncbi.nlm.nih.gov/pubmed/20040600
http://dx.doi.org/10.1074/jbc.M109.025981