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α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling

Antiangiogenesis therapies are now part of the standard repertoire of cancer therapies, but the mechanisms for the proliferation and survival of endothelial cells are not fully understood. Although endothelial cells are covered with a glycocalyx, little is known about how endothelial glycosylation r...

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Detalles Bibliográficos
Autores principales: Kitazume, Shinobu, Imamaki, Rie, Ogawa, Kazuko, Komi, Yusuke, Futakawa, Satoshi, Kojima, Soichi, Hashimoto, Yasuhiro, Marth, Jamey D., Paulson, James C., Taniguchi, Naoyuki
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825447/
https://www.ncbi.nlm.nih.gov/pubmed/20048157
http://dx.doi.org/10.1074/jbc.M109.073106