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Predicting highly-connected hubs in protein interaction networks by QSAR and biological data descriptors

Hub proteins (those engaged in most physical interactions in a protein interaction network (PIN) have recently gained much research interest due to their essential role in mediating cellular processes and their potential therapeutic value. It is straightforward to identify hubs if the underlying PIN...

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Detalles Bibliográficos
Autores principales: Hsing, Michael, Byler, Kendall, Cherkasov, Artem
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825595/
https://www.ncbi.nlm.nih.gov/pubmed/20198194