Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis

mPGES-1 (microsomal prostaglandin E synthase-1) is a stimulus-inducible enzyme that functions downstream of COX (cyclo-oxygenase)-2 in the PGE(2) (prostaglandin E(2))-biosynthesis pathway. Although COX-2-derived PGE(2) is known to play a role in the development of various tumours, the involvement of...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamei, Daisuke, Murakami, Makoto, Sasaki, Yuka, Nakatani, Yoshihito, Majima, Masataka, Ishikawa, Yukio, Ishii, Toshiharu, Uematsu, Satoshi, Akira, Shizuo, Hara, Shuntaro, Kudo, Ichiro
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825730/
https://www.ncbi.nlm.nih.gov/pubmed/19845504
http://dx.doi.org/10.1042/BJ20090045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825730/
https://www.ncbi.nlm.nih.gov/pubmed/19845504
http://dx.doi.org/10.1042/BJ20090045

Ejemplares similares