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Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis

mPGES-1 (microsomal prostaglandin E synthase-1) is a stimulus-inducible enzyme that functions downstream of COX (cyclo-oxygenase)-2 in the PGE(2) (prostaglandin E(2))-biosynthesis pathway. Although COX-2-derived PGE(2) is known to play a role in the development of various tumours, the involvement of...

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Detalles Bibliográficos
Autores principales:	Kamei, Daisuke, Murakami, Makoto, Sasaki, Yuka, Nakatani, Yoshihito, Majima, Masataka, Ishikawa, Yukio, Ishii, Toshiharu, Uematsu, Satoshi, Akira, Shizuo, Hara, Shuntaro, Kudo, Ichiro
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825730/ https://www.ncbi.nlm.nih.gov/pubmed/19845504 http://dx.doi.org/10.1042/BJ20090045

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