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Hematopoietic Stem Cell Differentiation Regulated by a Single Ubiquitin Ligase: Substrate Complex

Hematopoietic stem cell (HSC) differentiation is regulated by cell-intrinsic and extrinsic cues. In addition to transcriptional regulation, post-translational regulation may also control HSC differentiation. To test this hypothesis, we visualized ubiquitin-regulated protein stability of a single tra...

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Detalles Bibliográficos
Autores principales: Reavie, Linsey, Gatta, Giusy Della, Crusio, Kelly, Aranda-Orgilles, Beatriz, Buckley, Shannon M., Thompson, Benjamin, Lee, Eugine, Gao, Jie, Bredemeyer, Andrea L., Helmink, Beth A., Zavadil, Jiri, Sleckman, Barry P., Palomero, Teresa, Ferrando, Adolfo, Aifantis, Iannis
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825759/
https://www.ncbi.nlm.nih.gov/pubmed/20081848
http://dx.doi.org/10.1038/ni.1839