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The 2′-OH group at the group II intron terminus acts as a proton shuttle

Group II introns are self-splicing ribozymes that excise themselves from precursor RNAs and catalyze the joining of flanking exons. Excised introns can behave as parasitic RNA molecules, catalyzing their own insertion into DNA and RNA via a reverse-splicing reaction. Previous studies have identified...

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Detalles Bibliográficos
Autores principales: Roitzsch, Michael, Fedorova, Olga, Pyle, Anna Marie
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825881/
https://www.ncbi.nlm.nih.gov/pubmed/20118939
http://dx.doi.org/10.1038/nchembio.312