Cargando…

Attenuated Salmonella choleraesuis-mediated RNAi targeted to conserved regions against foot-and-mouth disease virus in guinea pigs and swine

In this study, specific sequences within three genes (3D, VP4 and 2B) of the foot-and-mouth disease virus (FMDV) genome were determined to be effective RNAi targets. These sequences are highly conserved among different serotype viruses based on sequence analysis. Small interfering RNA (siRNA)-expres...

Descripción completa

Detalles Bibliográficos
Autores principales: Cong, Wei, Jin, Hong, Jiang, Chengda, Yan, Weiyao, Liu, Mingqiu, Chen, Jiulian, Zuo, Xiaoping, Zheng, Zhaoxin
Formato: Texto
Lenguaje:English
Publicado: EDP Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826090/
https://www.ncbi.nlm.nih.gov/pubmed/20167192
http://dx.doi.org/10.1051/vetres/2010002