Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

BACKGROUND: Optineurin is a multifunctional protein involved in several functions such as vesicular trafficking from the Golgi to the plasma membrane, NF-κB regulation, signal transduction and gene expression. Mutations in optineurin are associated with glaucoma, a neurodegenerative eye disease that...

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Detalles Bibliográficos
Autores principales: Nagabhushana, Ananthamurthy, Chalasani, Madhavi L, Jain, Nishant, Radha, Vegesna, Rangaraj, Nandini, Balasubramanian, Dorairajan, Swarup, Ghanshyam
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826298/
https://www.ncbi.nlm.nih.gov/pubmed/20085643
http://dx.doi.org/10.1186/1471-2121-11-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826298/
https://www.ncbi.nlm.nih.gov/pubmed/20085643
http://dx.doi.org/10.1186/1471-2121-11-4

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