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Trigeminal injury causes kappa opioid-dependent allodynic, glial and immune cell responses in mice

BACKGROUND: The dynorphin-kappa opioid receptor (KOR) system regulates glial proliferation after sciatic nerve injury. Here, we investigated its role in cell proliferation following partial ligation of infraorbital nerve (pIONL), a model for trigeminal neuropathic pain. Mechanical allodynia was enha...

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Detalles Bibliográficos
Autores principales: Aita, Megumi, Byers, Margaret R, Chavkin, Charles, Xu, Mei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826348/
https://www.ncbi.nlm.nih.gov/pubmed/20109235
http://dx.doi.org/10.1186/1744-8069-6-8