Cargando…
Trigeminal injury causes kappa opioid-dependent allodynic, glial and immune cell responses in mice
BACKGROUND: The dynorphin-kappa opioid receptor (KOR) system regulates glial proliferation after sciatic nerve injury. Here, we investigated its role in cell proliferation following partial ligation of infraorbital nerve (pIONL), a model for trigeminal neuropathic pain. Mechanical allodynia was enha...
Autores principales: | Aita, Megumi, Byers, Margaret R, Chavkin, Charles, Xu, Mei |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826348/ https://www.ncbi.nlm.nih.gov/pubmed/20109235 http://dx.doi.org/10.1186/1744-8069-6-8 |
Ejemplares similares
-
Purple Corn Extract as Anti-allodynic Treatment for Trigeminal Pain: Role of Microglia
por: Magni, Giulia, et al.
Publicado: (2018) -
Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation
por: Chavkin, Charles, et al.
Publicado: (2019) -
CRF1-R Activation of the Dynorphin/Kappa Opioid System in the Mouse Basolateral Amygdala Mediates Anxiety-Like Behavior
por: Bruchas, Michael R., et al.
Publicado: (2009) -
Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward
por: Abraham, Antony D., et al.
Publicado: (2022) -
Anti-Allodynic Effects of Levodopa in Neuropathic Rats
por: Park, Hue Jung, et al.
Publicado: (2013)