The structural insights of stem cell factor receptor (c-Kit) interaction with tyrosine phosphatase-2 (Shp-2): An in silico analysis

BACKGROUND: Stem cell factor (SCF) receptor c-Kit is recognized as a key signaling molecule, which transduces signals for the proliferation, differentiation and survival of stem cells. Binding of SCF to its receptor triggers transactivation, leading to the recruitment of kinases and phosphatases to...

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Detalles Bibliográficos
Autores principales: Pati, Soumya, Gurudutta, Gangenahalli U, Kalra, Om P, Mukhopadhyay, Asok
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826351/
https://www.ncbi.nlm.nih.gov/pubmed/20205869
http://dx.doi.org/10.1186/1756-0500-3-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826351/
https://www.ncbi.nlm.nih.gov/pubmed/20205869
http://dx.doi.org/10.1186/1756-0500-3-14

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