Cargando…

Voltage-Dependent Gating in a “Voltage Sensor-Less” Ion Channel

The voltage sensitivity of voltage-gated cation channels is primarily attributed to conformational changes of a four transmembrane segment voltage-sensing domain, conserved across many levels of biological complexity. We have identified a remarkable point mutation that confers significant voltage de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurata, Harley T., Rapedius, Markus, Kleinman, Marc J., Baukrowitz, Thomas ., Nichols, Colin G.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826373/ https://www.ncbi.nlm.nih.gov/pubmed/20208975 http://dx.doi.org/10.1371/journal.pbio.1000315

Ejemplares similares

A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels
por: Schewe, Marcus, et al.
Publicado: (2016)

Voltage-Gated Lipid Ion Channels
por: Blicher, Andreas, et al.
Publicado: (2013)

Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels
por: Lau, Carus H. Y., et al.
Publicado: (2016)

Coupling between Voltage Sensors and Activation Gate in Voltage-gated K(+) Channels
por: Lu, Zhe, et al.
Publicado: (2002)

Thermodynamics of voltage-gated ion channels
por: Zhang, Xuejun C., et al.
Publicado: (2018)

Palmitoylation of Voltage-Gated Ion Channels
por: Cassinelli, Silvia, et al.
Publicado: (2022)

Pulsed Electric Fields Can Create Pores in the Voltage Sensors of Voltage-Gated Ion Channels
por: Rems, Lea, et al.
Publicado: (2020)

Coupled Movements in Voltage-gated Ion Channels
por: Horn, Richard
Publicado: (2002)

Regulating voltage-gated ion channels with nanobodies
por: Manning, Declan, et al.
Publicado: (2022)

Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor
por: Miranda, Pablo, et al.
Publicado: (2018)

Voltage- and cold-dependent gating of single TRPM8 ion channels
por: Fernández, José A., et al.
Publicado: (2011)

Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels
por: Pless, Stephan A, et al.
Publicado: (2013)

State-Dependent Network Connectivity Determines Gating in a K(+) Channel
por: Bollepalli, Murali K., et al.
Publicado: (2014)

Unconventional voltage sensing in an inwardly rectifying potassium channel
por: Kurata, Harley T.
Publicado: (2021)

Structure, gating and interactions of the voltage-dependent anion channel
por: Najbauer, Eszter E., et al.
Publicado: (2021)

Immobilizing the Moving Parts of Voltage-Gated Ion Channels
por: Horn, Richard, et al.
Publicado: (2000)

Thermodynamics of electromechanical coupling in voltage-gated ion channels
por: Chowdhury, Sandipan, et al.
Publicado: (2012)

Cnidarian Toxins Acting on Voltage-Gated Ion Channels
por: Messerli, Shanta M., et al.
Publicado: (2006)

Voltage-Gated Ion Channels in Cancer Cell Proliferation
por: Rao, Vidhya R., et al.
Publicado: (2015)

VGIchan: Prediction and Classification of Voltage-Gated Ion Channels
por: Saha, Sudipto, et al.
Publicado: (2006)

Editorial: Molecular Mechanisms of Voltage-Gating in Ion Channels
por: Loussouarn, Gildas, et al.
Publicado: (2021)

Voltage-Gated Ion Channels and the Variability in Information Transfer
por: Rathour, Rahul Kumar, et al.
Publicado: (2022)

Mechanisms of Ion Channels Voltage-Dependency: All about Molecular Sensors, Gates, Levers, Locks, and Grease
por: Loussouarn, Gildas, et al.
Publicado: (2012)

Lipid-dependent gating of a voltage-gated potassium channel
por: Zheng, Hui, et al.
Publicado: (2011)

Hysteresis in voltage-gated channels
por: Villalba-Galea, Carlos A.
Publicado: (2016)

Site and Mechanism of ML252 Inhibition of Kv7 Voltage-Gated Potassium Channels
por: Kanyo, Richard, et al.
Publicado: (2023)

Structure, Function and Modulation of Neuronal Voltage-Gated Ion Channels
por: Gribkoff, Valentin K, et al.
Publicado: (2008)

Mechanism of Ion Permeation in Mammalian Voltage-Gated Sodium Channels
por: Mahdavi, Somayeh, et al.
Publicado: (2015)

Guanidinium Toxins and Their Interactions with Voltage-Gated Sodium Ion Channels
por: Durán-Riveroll, Lorena M., et al.
Publicado: (2017)

Diabetes-induced changes in cardiac voltage-gated ion channels
por: Ozturk, Nihal, et al.
Publicado: (2021)

Molecular mechanism of voltage sensing in voltage-gated proton channels
por: Gonzalez, Carlos, et al.
Publicado: (2013)

Voltage-dependent gating of veratridine-modified Na channels
Publicado: (1986)

Cytoplasmic Domains and Voltage-Dependent Potassium Channel Gating
por: Barros, Francisco, et al.
Publicado: (2012)

Voltage-Dependent Gating of hERG Potassium Channels
por: Cheng, Yen May, et al.
Publicado: (2012)

Extracellular protons titrate voltage gating of a ligand-gated ion channel
por: Martínez-François, Juan Ramón, et al.
Publicado: (2010)

Voltage Gated Ion Channel Function: Gating, Conduction, and the Role of Water and Protons
por: Kariev, Alisher M., et al.
Publicado: (2012)

The Cooperative Voltage Sensor Motion that Gates a Potassium Channel
por: Pathak, Medha, et al.
Publicado: (2005)

A Hot Spot for the Interaction of Gating Modifier Toxins with Voltage-Dependent Ion Channels
por: Winterfield, Jeffrey R., et al.
Publicado: (2000)

Glial-dependent clustering of voltage-gated ion channels in Drosophila precedes myelin formation
por: Rey, Simone, et al.
Publicado: (2023)

Molecular Dynamics Simulations of Voltage-Gated Cation Channels: Insights on Voltage-Sensor Domain Function and Modulation
por: Delemotte, Lucie, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_s5ska5qie0r0djhe3irdi2584d