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A General Framework for Formal Tests of Interaction after Exhaustive Search Methods with Applications to MDR and MDR-PDT

The initial presentation of multifactor dimensionality reduction (MDR) featured cross-validation to mitigate over-fitting, computationally efficient searches of the epistatic model space, and variable construction with constructive induction to alleviate the curse of dimensionality. However, the met...

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Detalles Bibliográficos
Autores principales: Edwards, Todd L., Turner, Stephen D., Torstenson, Eric S., Dudek, Scott M., Martin, Eden R., Ritchie, Marylyn D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826406/
https://www.ncbi.nlm.nih.gov/pubmed/20186329
http://dx.doi.org/10.1371/journal.pone.0009363