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HAMLET Interacts with Lipid Membranes and Perturbs Their Structure and Integrity

BACKGROUND: Cell membrane interactions rely on lipid bilayer constituents and molecules inserted within the membrane, including specific receptors. HAMLET (human α-lactalbumin made lethal to tumor cells) is a tumoricidal complex of partially unfolded α-lactalbumin (HLA) and oleic acid that is intern...

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Detalles Bibliográficos
Autores principales: Mossberg, Ann-Kristin, Puchades, Maja, Halskau, Øyvind, Baumann, Anne, Lanekoff, Ingela, Chao, Yinxia, Martinez, Aurora, Svanborg, Catharina, Karlsson, Roger
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826418/
https://www.ncbi.nlm.nih.gov/pubmed/20186341
http://dx.doi.org/10.1371/journal.pone.0009384