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Canal Cristae Growth and Fiber Extension to the Outer Hair Cells of the Mouse Ear Require Prox1 Activity

BACKGROUND: The homeobox gene Prox1 is required for lens, retina, pancreas, liver, and lymphatic vasculature development and is expressed in inner ear supporting cells and neurons. METHODOLOGY/PRINCIPAL FINDINGS: We have investigated the role of Prox1 in the developing mouse ear taking advantage of...

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Detalles Bibliográficos
Autores principales: Fritzsch, Bernd, Dillard, Miriam, Lavado, Alfonso, Harvey, Natasha L., Jahan, Israt
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826422/
https://www.ncbi.nlm.nih.gov/pubmed/20186345
http://dx.doi.org/10.1371/journal.pone.0009377