Cargando…
Canal Cristae Growth and Fiber Extension to the Outer Hair Cells of the Mouse Ear Require Prox1 Activity
BACKGROUND: The homeobox gene Prox1 is required for lens, retina, pancreas, liver, and lymphatic vasculature development and is expressed in inner ear supporting cells and neurons. METHODOLOGY/PRINCIPAL FINDINGS: We have investigated the role of Prox1 in the developing mouse ear taking advantage of...
Autores principales: | Fritzsch, Bernd, Dillard, Miriam, Lavado, Alfonso, Harvey, Natasha L., Jahan, Israt |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826422/ https://www.ncbi.nlm.nih.gov/pubmed/20186345 http://dx.doi.org/10.1371/journal.pone.0009377 |
Ejemplares similares
-
Neurod1 Suppresses Hair Cell Differentiation in Ear Ganglia and Regulates Hair Cell Subtype Development in the Cochlea
por: Jahan, Israt, et al.
Publicado: (2010) -
Opportunities and limits of the one gene approach: the ability of Atoh1 to differentiate and maintain hair cells depends on the molecular context
por: Jahan, Israt, et al.
Publicado: (2015) -
Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation
por: Kersigo, Jennifer, et al.
Publicado: (2015) -
A Novel Atoh1 “Self-Terminating” Mouse Model Reveals the Necessity of Proper Atoh1 Level and Duration for Hair Cell Differentiation and Viability
por: Pan, Ning, et al.
Publicado: (2012) -
Incomplete and delayed Sox2 deletion defines residual ear neurosensory development and maintenance
por: Dvorakova, Martina, et al.
Publicado: (2016)