Cargando…

Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection

BACKGROUND: Human immunodeficiency virus (HIV) infection that persists despite antiretroviral therapy (ART) is a daunting problem. Given the limited evidence that resting CD4+ T cell infection (RCI) is affected by the histone deacetylase (HDAC) inhibitor valproic acid (VPA), we measured the stabilit...

Descripción completa

Detalles Bibliográficos
Autores principales: Archin, Nancie M., Cheema, Manzoor, Parker, Daniel, Wiegand, Ann, Bosch, Ronald J., Coffin, John M., Eron, Joseph, Cohen, Myron, Margolis, David M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826423/
https://www.ncbi.nlm.nih.gov/pubmed/20186346
http://dx.doi.org/10.1371/journal.pone.0009390