Escape from Human Monoclonal Antibody Neutralization Affects In Vitro and In Vivo Fitness of Severe Acute Respiratory Syndrome Coronavirus

Background. Severe acute respiratory syndrome (SARS) emerged as a human disease in 2002. Detailed phylogenetic analysis and epidemiologic studies have suggested that the SARS coronavirus (SARS-CoV) originated from animals. The spike (S) glycoprotein has been identified as a major target of protectiv...

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Detalles Bibliográficos
Autores principales: Rockx, Barry, Donaldson, Eric, Frieman, Matthew, Sheahan, Timothy, Corti, Davide, Lanzavecchia, Antonio, Baric, Ralph S.
Formato: Texto
Lenguaje:English
Publicado: The University of Chicago Press 2010
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826557/
https://www.ncbi.nlm.nih.gov/pubmed/20144042
http://dx.doi.org/10.1086/651022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826557/
https://www.ncbi.nlm.nih.gov/pubmed/20144042
http://dx.doi.org/10.1086/651022

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