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Coupling of receptor interference and a host-dependent post-binding entry deficiency in a gammaretroviral envelope protein
BACKGROUND: SL3-2 is a unique polytropic murine gammaretroviral isolate that is only able to infect murine cells. We have previously shown that two mutations R212G and T213I located on the surface of the receptor binding domain in a region designated the VR3 loop can alter the species tropism of thi...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827363/ https://www.ncbi.nlm.nih.gov/pubmed/20137084 http://dx.doi.org/10.1186/1742-4690-7-9 |