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Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells

BACKGROUND: Human multipotent mesenchymal stromal cells (MSC) can be isolated from various tissues including bone marrow. Here, MSC participate as bone lining cells in the formation of the hematopoietic stem cell niche. In this compartment, the oxygen tension is low and oxygen partial pressure is es...

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Detalles Bibliográficos
Autores principales: Holzwarth, Christina, Vaegler, Martin, Gieseke, Friederike, Pfister, Stefan M, Handgretinger, Rupert, Kerst, Gunter, Müller, Ingo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827377/
https://www.ncbi.nlm.nih.gov/pubmed/20109207
http://dx.doi.org/10.1186/1471-2121-11-11