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Incorporating demographic stochasticity into multi-strain epidemic models: application to influenza A
We develop mathematical models of the transmission and evolution of multi-strain pathogens that incorporate strain extinction and the stochastic generation of new strains via mutation. The dynamics resulting from these models is then examined with the applied aim of understanding the mechanisms unde...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827439/ https://www.ncbi.nlm.nih.gov/pubmed/19158010 http://dx.doi.org/10.1098/rsif.2008.0467 |