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In Vivo Detection of Extrapancreatic Insulin Gene Expression in Diabetic Mice by Bioluminescence Imaging

BACKGROUND: Extrapancreatic tissues such as liver may serve as potential sources of tissue for generating insulin-producing cells. The dynamics of insulin gene promoter activity in extrapancreatic tissues may be monitored in vivo by bioluminescence-imaging (BLI) of transgenic mice Tg(RIP-luc) expres...

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Detalles Bibliográficos
Autores principales: Chen, Xiaojuan, Larson, Courtney S., West, Jason, Zhang, Xiaomin, Kaufman, Dixon B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827564/
https://www.ncbi.nlm.nih.gov/pubmed/20195523
http://dx.doi.org/10.1371/journal.pone.0009397