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Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model

BACKGROUND: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a distinct subset of peptides and the enormous number of possible peptide epitopes prevents their complete experimental charact...

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Detalles Bibliográficos
Autores principales: Bordner, Andrew J, Mittelmann, Hans D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828437/
https://www.ncbi.nlm.nih.gov/pubmed/20089173
http://dx.doi.org/10.1186/1471-2105-11-41