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Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
BACKGROUND: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a distinct subset of peptides and the enormous number of possible peptide epitopes prevents their complete experimental charact...
Autores principales: | Bordner, Andrew J, Mittelmann, Hans D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828437/ https://www.ncbi.nlm.nih.gov/pubmed/20089173 http://dx.doi.org/10.1186/1471-2105-11-41 |
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