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Computational identification of rare codons of Escherichia coli based on codon pairs preference

BACKGROUND: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exogenous protein, have been defined by gene engineering operations. Previous studies have confirmed the existence of codon p...

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Detalles Bibliográficos
Autores principales: Wu, Xianming, Wu, Songfeng, Li, Dong, Zhang, Jiyang, Hou, Lin, Ma, Jie, Liu, Wanlin, Ren, Daming, Zhu, Yunping, He, Fuchu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828438/
https://www.ncbi.nlm.nih.gov/pubmed/20109184
http://dx.doi.org/10.1186/1471-2105-11-61