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A nuclear factor-binding domain in the 5'-untranslated region of the amyloid precursor protein promoter: Implications for the regulation of gene expression

BACKGROUND: The extracellular deposition of aggregated amyloid β-protein is a neuropathological manifestation of Alzheimer disease and Down syndrome. The Amyloid β-protein is derived from a group of larger differentially spliced proteins, the amyloid protein precursors (APP). Data suggests that the...

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Detalles Bibliográficos
Autores principales: Vostrov, Alexander A, Taheny, Michael J, Izkhakov, Nerik, Quitschke, Wolfgang W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828463/
https://www.ncbi.nlm.nih.gov/pubmed/20205906
http://dx.doi.org/10.1186/1756-0500-3-4